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Mutation Information
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Mutation Site
|
C632T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E7 |
|
Nucleotide_Mutation
|
T20I |
|
Genotype/Subtype
|
HPV58 |
|
Viral Reference
|
D90400.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
20870281
|
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Gynecologic oncology |
|
Title
|
Distribution of human papillomavirus 58 and 52 E6/E7 variants in cervical neoplasia in Chinese women. |
|
Author
|
Ding T,Wang X,Ye F,Cheng X,Ma D,Lu W,Xie X |
|
Evidence
|
For HPV58, the presence of C632T (T20I) and G760A (G63S) variants in E7 showed a positive trend of the association with the severity of neoplasia (P(trend)<0.05, chi2 test for trend).
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HPV Mutation Detail Information