Mutation Information
Mutation Site
|
C61S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
BPLF1 |
Literature Information
PubMed PMID
|
19244336
|
Published Year
|
2009 |
Journal
|
Journal of virology |
Title
|
The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity. |
Author
|
Whitehurst CB,Ning S,Bentz GL,Dufour F,Gershburg E,Shackelford J,Langelier Y,Pagano JS |
Evidence
|
Finally, expression of enzymatically active BPLF1 1-246 decreased RR activity, whereas a nonfunctional active-site mutant (BPLF1 C61S) had no effect.
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