Mutation Information
Mutation Site
|
C61R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
C |
Genotype/Subtype
|
A;C;F |
Literature Information
PubMed PMID
|
15661154
|
Disease
|
HBV infection
|
Published Year
|
2005 |
Journal
|
Virology |
Title
|
Effect of mutating the two cysteines required for HBe antigenicity on hepatitis B virus DNA replication and virion secretion. |
Author
|
Bang G,Kim KH,Guarnieri M,Zoulim F,Kawai S,Li J,Wands J,Tong S |
Evidence
|
Consistent with the detection of C61R genome from a patient serum, secretion block of the C61R mutant could be overcome by co-expression of wild-type core protein.
|
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