HBV Mutation Detail Information

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Mutation Information

Mutation Site	C52A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreS2
Country	China

Literature Information

PubMed PMID	21108338
Disease	Hepatocellular carcinoma
Published Year	2011
Journal	Journal of medical virology
Title	A matched case-control study of hepatitis B virus mutations in the preS and core promoter regions associated independently with hepatocellular carcinoma.
Author	Liu S,Xie J,Yin J,Zhang H,Zhang Q,Pu R,Li C,Ni W,Wang H,Cao G
Evidence	It was found that genotype C, HBeAg positivity, A2962G, and A109C/T were associated significantly with the risk of HCC, whereas abnormal albumin (≤35 g/L), C52A/T, and C105T were associated inversely with the risk of HCC.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation