HBV Mutation Detail Information

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Mutation Information
Mutation Site C481A
Mutation Type Nucleotide level
Gene/Protein/Region Type S
Combined Mutation s.L109I+rt.S117Y
Nucleotide_Mutation L109I
Genotype/Subtype A
Relevant Drug lamivudine (LAM)
Country Brazil
Literature Information
PubMed PMID 18171343
Disease Chronic hepatitis B
Published Year 2008
Journal Journal of gastroenterology and hepatology
Title Lamivudine resistance and other mutations in the polymerase and surface antigen genes of hepatitis B virus associated with a fatal hepatic failure case.
Author Bottecchia M,Ikuta N,Niel C,Araujo NM,O KM,Gomes SA
Evidence  In addition, three rare substitutions (at nt 481, 555, and 779) were detected in 2004, affecting the S protein (L109I, F134L, and I208T). 

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation