|
Mutation Information
|
Mutation Site
|
C335T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Nucleotide_Mutation
|
H78Y |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
NC_001526
|
|
Country
|
Congo |
Literature Information
|
PubMed PMID
|
25991921
|
|
Disease
|
Cervical carcinoma;
Squamous-cell carcinoma
|
|
Published Year
|
2015 |
|
Journal
|
Infectious agents and cancer |
|
Title
|
Genetic variability in E6 and E7 oncogenes of human papillomavirus Type 16 from Congolese cervical cancer isolates. |
|
Author
|
Boumba LM,Assoumou SZ,Hilali L,Mambou JV,Moukassa D,Ennaji MM |
|
Evidence
|
The most frequently observed nucleotide variations were the missense C143G, G145T and C335T in E6 (100%), leading to the non-synonymous amino acid variation Q14D and H78Y.
|
|
|
HPV Mutation Detail Information