|
Mutation Information
|
Mutation Site
|
C335T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Nucleotide_Mutation
|
H78Y |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
Literature Information
|
PubMed PMID
|
22524831
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2012 |
|
Journal
|
Asian Pacific journal of cancer prevention : APJCP |
|
Title
|
Whole genome analysis of human papillomavirus type 16 multiple infection in cervical cancer patients. |
|
Author
|
Chansaenroj J,Theamboonlers A,Junyangdikul P,Swangvaree S,Karalak A,Poovorawan Y |
|
Evidence
|
The E6 gene of the 8 whole genome sequences showed 7 mutation points; 3 (42.9%) were synonymous mutations while 4 (57.1%) were non synonymous mutations with amino acid substitutions at Q14H (nt G145T), D25E (nt T178G), H78Y (nt C335T), L83V (nt T350G) (Table 2).
|
|
|
HPV Mutation Detail Information