|
Mutation Information
|
Mutation Site
|
C335T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Nucleotide_Mutation
|
H78Y |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
19358280
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2009 |
|
Journal
|
International journal of cancer |
|
Title
|
Molecular variants of HPV-16 associated with cervical cancer in Indian population. |
|
Author
|
Pillai MR,Hariharan R,Babu JM,Lakshmi S,Chiplunkar SV,Patkar M,Tongaonkar H,Dinshaw K,Jayshree RS,Reddy BK,Siddiqui M,Roychoudury S,Saha B,Abraham P,Gnanamony M,Peedicayil A,Subhashini J,Ram TS,Dey B,Sharma C,Jain SK,Singh N |
|
Evidence
|
The other nonsynonymous changes seen in all the centres were G145T which led to an amino acid change of Q14H and was seen in 13.1% of the samples, and a change of C335T which led to an amino acid change of H78Y was seen in 12.1% of the samples.
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HPV Mutation Detail Information