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Mutation Information
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Mutation Site
|
C3116T |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
|
PreS |
|
Nucleotide_Mutation
|
A90V |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
M12906
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
19272629
|
|
Clinical information
|
Yes
|
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Disease
|
HBV infection
|
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Published Year
|
2009 |
|
Journal
|
Virology |
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Title
|
Association between genomic heterogeneity of hepatitis B virus and intrauterine infection. |
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Author
|
Cheng H,Su H,Wang S,Shao Z,Men K,Li M,Li S,Zhang J,Xu J,Zhang H,Yan Y,Xu D |
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Evidence
|
Five of these six mutations may be mainly divided into two types: (1) C3116T and C705T mutations, which were detected in all clones isolated from group C, but emerged with lower proportions in groups M and N; and (2) C3175T, C96T and T473C mutations, which were detected in clones isolated from one mother (M4) in group M and four infected neonates (N2, 3, 7 and 8) in group N, but not in clones isolated from mothers in group C.
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HBV Mutation Detail Information