|
Mutation Information
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Mutation Site
|
C2946G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreS |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
20419326
|
|
Disease
|
HBV infection;
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma. |
|
Author
|
Yin J,Xie J,Zhang H,Shen Q,Han L,Lu W,Han Y,Li C,Ni W,Wang H,Cao G |
|
Evidence
|
The risk of variables, containing age, sex (female vs. male), HBV DNA level (≥104 vs. <104 copies/mL), genotype (C vs. B), ALT (abnormal vs. normal), HBeAg status (positive vs. negative), and the presence of A2964C, T/A2875C, C2946G, C53T, and T3116C for LC were determined by the multivariate regression analysis.
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HBV Mutation Detail Information