Mutation Information
Mutation Site
|
C28A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
BILF1 |
Literature Information
PubMed PMID
|
30647152
|
Published Year
|
2019 |
Journal
|
mBio |
Title
|
Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation. |
Author
|
Fares S,Spiess K,Olesen ETB,Zuo J,Jackson S,Kledal TN,Wills MR,Rosenkilde MM |
Evidence
|
The cysteine mutants C97A, C174A, C28A, and C258A showed impaired MHC class I downregulation, where they reduced MHC class I surface level by ∼20% (Fig. 4A and andB).B).
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