Mutation Information
Mutation Site
|
C2875A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreS |
Country
|
China |
Literature Information
PubMed PMID
|
21104161
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2010 |
Journal
|
Frontiers of medicine in China |
Title
|
Association of novel mutations and haplotypes in the preS region of hepatitis B virus with hepatocellular carcinoma. |
Author
|
Xie JX,Zhao J,Yin JH,Zhang Q,Pu R,Lu WY,Zhang HW,Wang HY,Cao GW |
Evidence
|
C2875A, G2950A, G2951A, A3054T, C3060T, T3066A, T3069G, A3120T, and G3191C were significantly associated with increased risks of HCC in genotype C, whereas these mutations were inversely associated with HCC in genotype B.
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