HPV Mutation Detail Information

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Mutation Information
Mutation Site C2859A
Mutation Type Nucleotide level
Gene/Protein/Region Type E2
Nucleotide_Mutation H35Q
Genotype/Subtype HPV16
Country Romania
Literature Information
PubMed PMID 25143263
Disease Cervical carcinoma; Squamous-cell carcinoma; Cervical intraepithelial neoplasia
Published Year 2014
Journal Archives of virology
Title Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients.
Author Plesa A,Anton G,Iancu IV,Diaconu CC,Huica I,Stanescu AD,Socolov D,Nistor E,Popa E,Stoian M,Botezatu A
Evidence In the transactivation domain, the substitutions C2859A (H35Q), G2890T (A46S), C3158A (T135K) and G3181A (A143T) were found, and within the hinge domain, A3361G (N203D), C3376G (P208A), T3386C (I211T), A3395G (H214R), C3409T (P219L), C3437A (A228D), G3448A (E232K), C3515A (T254N), T3516C (T254N), G3459A (Q235-), A3489G (P245-), A3537C (S261) and T3565G (F271V).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation