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HPV Mutation Detail Information

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Mutation Information
Mutation Site C24G
Mutation Type Amino acid level
Gene/Protein/Region Type E7
Genotype/Subtype HPV16
Literature Information
PubMed PMID 12196821
Published Year 2002
Journal Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
Title [Modification of HPV type 16 E6 and E7 genes, and analysis of stability and immunogenicity of the modified proteins].
Author Zhi H,Han L,Ren J,Tian H,Luo W,Liang Y,Ruan L
Evidence Western blot assay showed that the E6 mutant with substitution of Gly for Leu at amino acid site 50 and E7 mutant with substitution of Gly for Cys-24 and Glu-26 had no effect on their stability and antigenicity, but change of the Cys at position 91 of E7 dramatically reduced its stability and antigencity.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation