HPV Mutation Detail Information

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Mutation Information
Mutation Site C24G
Mutation Type Amino acid level
Gene/Protein/Region Type E7
Genotype/Subtype HPV16
Literature Information
PubMed PMID 11543887
Published Year 2001
Journal Journal of virological methods
Title Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay.
Author Dong WL,Caldeira S,Sehr P,Pawlita M,Tommasino M
Evidence Point mutation C24G in the high affinity pRb-binding domain of HPV16 E7 results in a 3-fold affinity reduction.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation