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Mutation Information
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Mutation Site
|
C2237G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E1 |
|
Nucleotide_Mutation
|
T458S |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
Greek |
Literature Information
|
PubMed PMID
|
23881083
|
|
Disease
|
Cervical carcinoma;
Cervical intraepithelial neoplasia
|
|
Published Year
|
2014 |
|
Journal
|
Archives of virology |
|
Title
|
Nucleotide polymorphisms of the human papillomavirus 16 E1 gene. |
|
Author
|
Tsakogiannis D,Darmis F,Gortsilas P,Ruether IG,Kyriakopoulou Z,Dimitriou TG,Amoutzias G,Markoulatos P |
|
Evidence
|
In addition sequence analysis of the E1 region revealed the nucleotide variations C2041T, G2220C, C2237G, G2249A, C2262T, C2287T and C2344T, from which the nucleotide variations C2041T, G2220C, C2237G, and G2249A induced the amino acid changes L393I, E425D, T458S, and R462K, while the C2262T, C2287T, and C2344T changes were silent nucleotide variations.
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HPV Mutation Detail Information