Mutation Information
Mutation Site
|
C206E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
BMRF1 |
Literature Information
PubMed PMID
|
20926567
|
Published Year
|
2010 |
Journal
|
Journal of virology |
Title
|
Tetrameric ring formation of Epstein-Barr virus polymerase processivity factor is crucial for viral replication. |
Author
|
Nakayama S,Murata T,Yasui Y,Murayama K,Isomura H,Kanda T,Tsurumi T |
Evidence
|
Also, surprisingly, replication of the C206E virus, which is expected to have impairment of tail-to-tail contact, was severely restricted, although the mutant protein possesses the same in vitro biochemical activities as the wild type.
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