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Mutation Information
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Mutation Site
|
C206E |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BMRF1 |
Literature Information
|
PubMed PMID
|
20926567
|
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Published Year
|
2010 |
|
Journal
|
Journal of virology |
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Title
|
Tetrameric ring formation of Epstein-Barr virus polymerase processivity factor is crucial for viral replication. |
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Author
|
Nakayama S,Murata T,Yasui Y,Murayama K,Isomura H,Kanda T,Tsurumi T |
|
Evidence
|
Also, surprisingly, replication of the C206E virus, which is expected to have impairment of tail-to-tail contact, was severely restricted, although the mutant protein possesses the same in vitro biochemical activities as the wild type.
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