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Mutation Information
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Mutation Site
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C193Y |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Nef |
Literature Information
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PubMed PMID
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31927483
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Published Year
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2020 |
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Journal
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iScience |
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Title
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Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation. |
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Author
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Hirao K,Andrews S,Kuroki K,Kusaka H,Tadokoro T,Kita S,Ose T,Rowland-Jones SL,Maenaka K |
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Evidence
|
Dotted circles indicate distinct structures determined in HIV-2 and SIVmac Nefs. HIV-2 Nef proteins (wild-type and C193Y mutant) were expressed in Escherichia coli as soluble proteins and purified to show a single peak by size exclusion chromatography as a monomer (Figure S1A).
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HIV Mutation Detail Information