EBV Mutation Detail Information

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Mutation Information

Mutation Site	C189V
Mutation Type	Amino acid level
Gene/Protein/Region Type	Zta

Literature Information

PubMed PMID	29772230
Published Year	2018
Journal	Biochemical and biophysical research communications
Title	Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double-stranded DNA.
Author	Ray S,Tillo D,Assad N,Ufot A,Deppmann C,Durell SR,Porollo A,Vinson C
Evidence	Zta(C189A) and Zta(C189V) had higher non-specific binding to all four types of DNA. Our data suggests that position C189 in Zta impacts sequence-specific binding to DNA containing modified and unmodified cytosine.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation