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Mutation Information
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Mutation Site
|
C189S |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BZLF1 |
Literature Information
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PubMed PMID
|
18305033
|
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Published Year
|
2008 |
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Journal
|
Journal of virology |
|
Title
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Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication. |
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Author
|
Wiedmer A,Wang P,Zhou J,Rennekamp AJ,Tiranti V,Zeviani M,Lieberman PM |
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Evidence
|
A point mutation in the Zta DNA binding domain (C189S), which is known to reduce lytic cycle replication, eliminated mtSSB association with Zta.
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EBV Mutation Detail Information