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Mutation Information
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Mutation Site
|
C1869T |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreC |
Literature Information
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PubMed PMID
|
21742757
|
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Clinical information
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Yes
|
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Disease
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Chronic hepatitis B
|
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Published Year
|
2011 |
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Journal
|
Nucleic acids research |
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Title
|
Ultra-deep pyrosequencing analysis of the hepatitis B virus preCore region and main catalytic motif of the viral polymerase in the same viral genome. |
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Author
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Homs M,Buti M,Quer J,Jardí R,Schaper M,Tabernero D,Ortega I,Sanchez A,Esteban R,Rodriguez-Frias F |
|
Evidence
|
Additionally, the low percentage (0.1%) of G to A changes in Position 1891, which represent a new stop codon in the preCore sequence (W26stop), were also compensated by a complementary C to T change in a similar percentage (0.09%) in the base-paired C1869T position.
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HBV Mutation Detail Information