HPV Mutation Detail Information

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Mutation Information
Mutation Site C185S
Mutation Type Amino acid level
Gene/Protein/Region Type L1
Genotype/Subtype HPV16
Literature Information
PubMed PMID 21811610
Published Year 2011
Journal PloS one
Title Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16.
Author Conway MJ,Cruz L,Alam S,Christensen ND,Meyers C
Evidence Specifically, the C175S substitution severely undermined wild-type titers of the virus within both 10 and 20-day tissue, while C428S, C185S, and C175,185S substitutions severely undermined wild-type titers only within 20-day tissue.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation