Mutation Information
Mutation Site
|
C1858T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Country
|
Indonesia |
Literature Information
PubMed PMID
|
31086664
|
Disease
|
HBV associated liver disease
|
Published Year
|
2019 |
Journal
|
Biomedical reports |
Title
|
Analysis of hepatitis B virus genotype and gene mutation in patients with advanced liver disease in East Kalimantan, Indonesia. |
Author
|
Wahyuni RM,Utsumi T,Juniastuti,Yano Y,Murti IS,Amin M,Yamani LN,Istimagfiroh A,Purwono PB,Soetjipto,Lusida MI,Hayashi Y |
Evidence
|
The C1505A mutation in X region, T1753V and A1762T/G1764A mutations in the basal core promoter region and C1858T in precore (PC) region were frequent and only detected in patients with ALD (28.9, 40, 73.5 and 17.6%, respectively), whereas the G1896A mutation in the PC region was frequently detected in HBV carriers.
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