|
Mutation Information
|
Mutation Site
|
C1858T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Viral Reference
|
AY233274.1
|
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
23029487
|
|
Clinical information
|
Yes
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Genotyping and molecular characterization of hepatitis B virus from human immunodeficiency virus-infected individuals in southern Africa. |
|
Author
|
Makondo E,Bell TG,Kramvis A |
|
Evidence
|
Mutations affecting HBeAg expression at the transcriptional (1762T1764A), translational (Kozak 1809-1812, initiation 1814-1816, G1896A with C1858T), or post translational levels (G1862T), were responsible for the high HBeAg-negativity observed.
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HBV Mutation Detail Information