Mutation Information
Mutation Site
|
C1858T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Genotype/Subtype
|
A;D;F |
Country
|
Brazil |
Literature Information
PubMed PMID
|
15572007
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2005 |
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
Title
|
The precore mutation is associated with severity of liver damage in Brazilian patients with chronic hepatitis B. |
Author
|
Rezende RE,Fonseca BA,Ramalho LN,Zucoloto S,Pinho JR,Bertolini DA,Martinelli AL |
Evidence
|
All patients infected with the G1896A precore mutant variant, genotype A, presented the association of a second mutation, i.e. an exchange of cytosine with thymine, in the position of nucleotide 1858, codon 15 (C1858T).
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