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Mutation Information
|
Mutation Site
|
C1766T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.C1766T+bcp.G1764A+bcp.A1762T |
|
Viral Reference
|
AY090460;
AY090457;
AY090454;
AF405706;
AB064310;
AF160501;
AF223965;
AB036910;
X69798;
;
AB032431;
X75657;
X85254;
M32138;
X65259;
AB014381;
M12906;
X04615;
AB033554;
AF100309;
D00329;
AF090842;
X51970;
X02763 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
20070500
|
|
Disease
|
Acute on chronic liver failure
|
|
Published Year
|
2010 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis. |
|
Author
|
Ren X,Xu Z,Liu Y,Li X,Bai S,Ding N,Zhong Y,Wang L,Mao P,Zoulim F,Xu D |
|
Evidence
|
Single mutations including T1753V (C/A/G), A1762T, G1764A, G1896A and G1899A and triple mutations T1753V/A1762T/G1764A and A1762T/G1764A/C1766T (or T1768A) were more frequently detected in patients with HB-ACLF than in patients with CHB.
|
|
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HBV Mutation Detail Information