Mutation Information
Mutation Site
|
C175S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
L1 |
Genotype/Subtype
|
HPV16 |
Literature Information
PubMed PMID
|
25096873
|
Published Year
|
2014 |
Journal
|
mBio |
Title
|
Maturation of the human papillomavirus 16 capsid. |
Author
|
Cardone G,Moyer AL,Cheng N,Thompson CD,Dvoretzky I,Lowy DR,Schiller JT,Steven AC,Buck CB,Trus BL |
Evidence
|
A C175S mutant that cannot achieve normal inter-L1 disulfide cross-links shows maturation-related shrinkage but does not achieve the fully condensed 60-nm form.
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