Mutation Information
Mutation Site
|
C175S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
L1 |
Genotype/Subtype
|
HPV16 |
Literature Information
PubMed PMID
|
24918586
|
Published Year
|
2014 |
Journal
|
PloS one |
Title
|
Roles for human papillomavirus type 16 l1 cysteine residues 161, 229, and 379 in genome encapsidation and capsid stability. |
Author
|
Ryndock EJ,Conway MJ,Alam S,Gul S,Murad S,Christensen ND,Meyers C |
Evidence
|
We had previously described some cysteine mutants designed to prevent inter-pentameric disulfide bonding (C175S and C185S) that increased in infectivity from 10 to 20 days of tissue growth.
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