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Mutation Information
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Mutation Site
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C1727G |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
EnhII |
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Country
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China |
Literature Information
|
PubMed PMID
|
20959817
|
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
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Published Year
|
2011 |
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Journal
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The American journal of gastroenterology |
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Title
|
Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. |
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Author
|
Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G |
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Evidence
|
HBV genotype (C vs. B), ALT (abnormal vs. normal), HBeAg status (positive vs. negative), and the presence of C1673T, A1703G, A1726C, C1727G, A1762T / G1764A, C1766T, T1768A, C1773T, A1846T, and G1896A were introduced into the multivariate regression model.
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HBV Mutation Detail Information