|
Mutation Information
|
Mutation Site
|
C168S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E1 |
|
Amino acid_Mutation
|
T1366A |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
Greek |
Literature Information
|
PubMed PMID
|
23881083
|
|
Disease
|
Cervical carcinoma;
Cervical intraepithelial neoplasia
|
|
Published Year
|
2014 |
|
Journal
|
Archives of virology |
|
Title
|
Nucleotide polymorphisms of the human papillomavirus 16 E1 gene. |
|
Author
|
Tsakogiannis D,Darmis F,Gortsilas P,Ruether IG,Kyriakopoulou Z,Dimitriou TG,Amoutzias G,Markoulatos P |
|
Evidence
|
The nucleotide changes T921C, T1200C, C1377T and T1486C do not cause amino acid substitutions in the E1 protein, while the nucleotide changes C1096G, G1163A, T1366A and C1426G result in the amino acid changes Q78E, G100E, C168S and Q188E, respectively.
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HPV Mutation Detail Information