HBV Mutation Detail Information

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Mutation Information
Mutation Site C1673T
Mutation Type Nucleotide level
Gene/Protein/Region Type C Promoter
Genotype/Subtype C
Country China
Literature Information
PubMed PMID 20959817
Disease Chronic hepatitis B; Liver cirrhosis; Hepatocellular carcinoma
Published Year 2011
Journal The American journal of gastroenterology
Title Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma.
Author Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G
Evidence C1673T, A1726C, A1727T, C1730G, C1766T, T1768A, C1773T, and C1799G in genotype C were significantly associated with cirrhosis compared with the CHB patients, whereas these mutations were inversely associated with HCC compared with the cirrhosis patients.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation