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Mutation Information
|
Mutation Site
|
C1653V |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
20820820
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2011 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan. |
|
Author
|
Kusakabe A,Tanaka Y,Inoue M,Kurbanov F,Tatematsu K,Nojiri S,Joh T,Tsugane S,Mizokami M |
|
Evidence
|
To identify the independent risk factors associated with the development of HCC, the following factors were evaluated by using multivariate-adjusted Cox hazard model among HBV mono-infected subjects: age, gender, BMI, alcohol intake, smoking, ALT, γ-GTP, HBeAg positivity, HBcrAg positivity, HBV DNA ≥ 5 log copies/mL, genotype (C2/Ce or not), and HBV specific mutations (C1653 V, T1753 V, A1762T/G1764A and G1896A).
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HBV Mutation Detail Information