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Mutation Information
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Mutation Site
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C1653T |
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Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
EnhII |
|
Viral Reference
|
FJ904433.1;
GQ924620.1;
AB219428.1;
EU054331.1 |
Literature Information
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PubMed PMID
|
31324819
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2019 |
|
Journal
|
Scientific reports |
|
Title
|
Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients. |
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Author
|
Podlaha O,Gane E,Brunetto M,Fung S,Chuang WL,Pan CQ,Jiang Z,Liu Y,Bhardwaj N,Mukherjee P,Flaherty J,Gaggar A,Subramanian M,Izumi N,Shalimar,Lim YS,Marcellin P,Buti M,Chan HLY,Agarwal K |
|
Evidence
|
Aside from C1817T and A1838G variants, it is worth mentioning that C1653T, G1896A, and G1899A displayed the next most significant association with viral load in the discovery patient cohort (LRT p = 6 × 10−8, p = 6.7 × 10−8, and p = 2.3 × 10−7, respectively)
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HBV Mutation Detail Information