HBV Mutation Detail Information

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Mutation Information

Mutation Site	C1653T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	EnhII
Country	China

Literature Information

PubMed PMID	27075395
Disease	Hepatocellular carcinoma
Published Year	2016
Journal	Cancer medicine
Title	Hepatitis B virus mutations, expression quantitative trait loci for PTPN12, and their interactions in hepatocellular carcinoma.
Author	Song C,Liu Y,Xu L,Wen J,Jiang D,Chen J,Zhai X,Hu Z,Liu L,Liu J
Evidence	Of those 19 hotspot mutations, C1653T, T1674C/G, A1703G, G1719T, T1727A/G, T1753C, A1762T, G1764A, G1799C, G1899A, G1915A/C, and C1969T were significantly associated with an increased risk of HCC, whereas C1673T, A1726C, C1730G, and A1752G were significantly associated with a reduced risk of HCC, when adjusted for age and gender

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation