|
Mutation Information
|
Mutation Site
|
C1653T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Genotype/Subtype
|
C2 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26290395
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2015 |
|
Journal
|
Cancer prevention research (Philadelphia, Pa.) |
|
Title
|
Hepatitis B Virus Combo Mutations Improve the Prediction and Active Prophylaxis of Hepatocellular Carcinoma: A Clinic-Based Cohort Study. |
|
Author
|
Yin J,Wang J,Pu R,Xin H,Li Z,Han X,Ding Y,Du Y,Liu W,Deng Y,Ji X,Wu M,Yu M,Zhang H,Wang H,Thompson TC,Ni W,Cao G |
|
Evidence
|
Multivariate Cox regression analyses, including baseline characteristics of 2,114 patients, showed that age, male, cirrhosis, and HBV mutations (C1653T, T1753V, and A1762T/G1764A) independently increased HCC risk.
|
|
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HBV Mutation Detail Information