Mutation Information
Mutation Site
|
C1653T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
C Promoter |
Country
|
Morocco |
Literature Information
PubMed PMID
|
22905181
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2012 |
Journal
|
PloS one |
Title
|
Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression. |
Author
|
Kitab B,Essaid El Feydi A,Afifi R,Trepo C,Benazzouz M,Essamri W,Zoulim F,Chemin I,Alj HS,Ezzikouri S,Benjelloun S |
Evidence
|
CP mutations C1653T, T1753V, A1762T/G1764A, and C1766T/T1768A were associated with higher HBV-DNA level and increased liver disease severity.
|
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