|
Mutation Information
|
Mutation Site
|
C1653T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Genotype/Subtype
|
C;A;B;C2;B2;C1 |
|
Country
|
Korea;Japan;Philippines;ChiUnitedStates;HongKong;Vietnam |
Literature Information
|
PubMed PMID
|
19574418
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2009 |
|
Journal
|
Journal of the National Cancer Institute |
|
Title
|
Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis. |
|
Author
|
Liu S,Zhang H,Gu C,Yin J,He Y,Xie J,Cao G |
|
Evidence
|
Statistically significant summary odds ratios of HCC were obtained for any PreS mutation (3.77, 95% confidence interval [CI] = 2.57 to 5.52), C1653T in EnhII (2.76, 95% CI = 2.09 to 3.64), T1753V (2.35, 95% CI = 1.63 to 3.40), and A1762T/G1764A in BCP (3.79, 95% CI = 2.71 to 5.29).
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HBV Mutation Detail Information