|
Mutation Information
|
Mutation Site
|
C1653T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Genotype/Subtype
|
C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
10481738
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
1999 |
|
Journal
|
Archives of virology |
|
Title
|
Clinical implications of mutations C-to-T1653 and T-to-C/A/G1753 of hepatitis B virus genotype C genome in chronic liver disease. |
|
Author
|
Takahashi K,Ohta Y,Kanai K,Akahane Y,Iwasa Y,Hino K,Ohno N,Yoshizawa H,Mishiro S |
|
Evidence
|
Among many mutational hot spots on hepatitis B virus (HBV) genome, A-to-T1762 and G-to-A1764 within the core promoter have been underscored in view of disease association as well as viral expression/replication.
|
|
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HBV Mutation Detail Information