HBV Mutation Detail Information

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Mutation Information

Mutation Site	C149S
Mutation Type	Amino acid level
Gene/Protein/Region Type	S

Literature Information

PubMed PMID	19759159
Published Year	2009
Journal	Journal of virology
Title	The pre-S1 and antigenic loop infectivity determinants of the hepatitis B virus envelope proteins are functionally independent.
Author	Le Duff Y,Blanchet M,Sureau C
Evidence	Such lesions consisted in a small deletion (Δ119-123) or single amino acid substitutions (I110A, P120A, R122A, C139S, K141A, P142A, C147S, C149S, I150A, P153A, and W156A), which have been described previously as drastically reducing HDV infectivity when present in all three S-, M-, and L-HBsAg proteins (2, 39).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation