HPV Mutation Detail Information

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Mutation Information
Mutation Site C143G
Mutation Type Nucleotide level
Gene/Protein/Region Type E6
Nucleotide_Mutation Q14D
Genotype/Subtype HPV16
Viral Reference NC_001526
Country Congo
Literature Information
PubMed PMID 25991921
Disease Cervical carcinoma; Squamous-cell carcinoma
Published Year 2015
Journal Infectious agents and cancer
Title Genetic variability in E6 and E7 oncogenes of human papillomavirus Type 16 from Congolese cervical cancer isolates.
Author Boumba LM,Assoumou SZ,Hilali L,Mambou JV,Moukassa D,Ennaji MM
Evidence The most frequently observed nucleotide variations were the missense C143G, G145T and C335T in E6 (100%), leading to the non-synonymous amino acid variation Q14D and H78Y.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation