HBV Mutation Detail Information

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Mutation Information

Mutation Site	C135T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreS2
Country	China

Literature Information

PubMed PMID	21108338
Disease	Hepatocellular carcinoma
Published Year	2011
Journal	Journal of medical virology
Title	A matched case-control study of hepatitis B virus mutations in the preS and core promoter regions associated independently with hepatocellular carcinoma.
Author	Liu S,Xie J,Yin J,Zhang H,Zhang Q,Pu R,Li C,Ni W,Wang H,Cao G
Evidence	PreS2 start codon mutation, preS2 deletion, C1A/G, T53C, C135A/T, and A1762T were associated significantly with an increased risk of HCC in both genotypes.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation