HBV Mutation Detail Information

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Mutation Information
Mutation Site C124N
Mutation Type Amino acid level
Gene/Protein/Region Type S
Combined Mutation s.G130R+s.C124N+s.N146S
Viral Reference D00630; M54923; HPBAYW
Immune Escape Y
Relevant Drug fludarabine
Country Greek
Literature Information
PubMed PMID 16789016
Disease HBV infection
Published Year 2006
Journal Journal of medical virology
Title Detection of a hepatitis B surface antigen variant emerging in a patient with chronic lymphocytic leukaemia treated with fludarabine.
Author Alexopoulou A,Dourakis SP,Pandelidaki H,Archimandritis AJ,Karayiannis P
Evidence Amino-acid sequence comparisons over the alpha determinant region revealed the following substitutions: C124N, G130R, and N146S. There were also unique substitutions outside the alpha determinant. 

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation