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Mutation Information
|
Mutation Site
|
C1225T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E1 |
|
Nucleotide_Mutation
|
E121D |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718;
AF536179;
HQ644236;
AF534061;
AF536180;
HQ644298;
AF472509;
HQ644257;
AY686579;
AF402678 |
|
Country
|
Poland |
Literature Information
|
PubMed PMID
|
33909391
|
|
Disease
|
Low grade squamous intraepithelial lesion
|
|
Published Year
|
2021 |
|
Journal
|
Acta biochimica Polonica |
|
Title
|
Sequence variation analysis of the E1 and E2 genes of human papillomavirus type 16 in cervical lesions in women from the south of Poland. |
|
Author
|
Sitarz K,Kopec J,Zawilinska B,Klimek M,Szostek S |
|
Evidence
|
The sequence analysis showed substitutions at 7 nucleotides located between positions 1053 and 2456 (A1053C, G1189T, G1222A, C1225T, G1345C, A1892C, G2034T) leading to an amino acid change (E63D, R109I, R120K, E121D, S161T, Q343H, A391S), while another nucleotide substitution (C2456T) was silent.
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HPV Mutation Detail Information