|
Mutation Information
|
Mutation Site
|
C105T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
25501679
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2015 |
|
Journal
|
Clinical and experimental medicine |
|
Title
|
Association between HBV Pre-S mutations and the intracellular HBV DNAs in HBsAg-positive hepatocellular carcinoma in China. |
|
Author
|
Wang H,Wang AH,Gressner OA,Fang M,Gu X,Ji Q,Cheng SQ,Shen F,Gao CF |
|
Evidence
|
Three Pre-S mutants (A2962G and C2964A in Pre-S1 and C105T in Pre-S2) were associated with higher tumor cccDNA levels (P < 0.05), and A2962G/C2964A mutants were associated with higher AFP levels
|
|
|
HBV Mutation Detail Information