HIV Mutation Detail Information

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Mutation Information

Mutation Site	A98G
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Thailand

Literature Information

PubMed PMID	22132100
Disease	HIV infection/AIDS
Published Year	2011
Journal	PloS one
Title	Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis.
Author	Ngo-Giang-Huong N,Jourdain G,Amzal B,Sang-a-gad P,Lertkoonalak R,Eiamsirikit N,Tansuphasawasdikul S,Buranawanitchakorn Y,Yutthakasemsunt N,Mekviwattanawong S,McIntosh K,Lallemant M,Program for HIV Prevention and Treatment (PHPT) study group.
Evidence	Longer duration of failure was also significantly associated with higher risk of M184V (PP[OR>1] = 94%) and NNRTI mutations G190A (PP[OR>1] = 95%), K101E (PP[OR>1] = 94%) and A98G (PP[OR>1] = 99%). Occurrence of K103N was associated with shorter duration of failure (PP[OR<1] = 97%).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation