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Mutation Information
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Mutation Site
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A92E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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CA |
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Relevant Drug
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IFN-beta |
Literature Information
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PubMed PMID
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31511380
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Published Year
|
2019 |
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Journal
|
Journal of virology |
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Title
|
Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid. |
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Author
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Sultana T,Mamede JI,Saito A,Ode H,Nohata K,Cohen R,Nakayama EE,Iwatani Y,Yamashita M,Hope TJ,Shioda T |
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Evidence
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Next, we examined the relationship between the A92E CA mutation and the G116R mutation since the NL4-3 A92E CA mutant shares several phenotypes with the NL4-3 G94D CA mutant in terms of sensitivity to CypA and an inability to infect nondividing cells.
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HIV Mutation Detail Information