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Mutation Information
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Mutation Site
|
A82G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E7 |
|
Combined Mutation
|
e7.A82G+e7.T278C |
|
Nucleotide_Mutation
|
M28V |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26192265
|
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
|
Published Year
|
2016 |
|
Journal
|
Journal of medical virology |
|
Title
|
Distribution of human papilloma virus type 16 E6/E7 gene mutation in cervical precancer or cancer: A case control study in Guizhou Province, China. |
|
Author
|
Yang Y,Ren J,Zhang Q |
|
Evidence
|
The resultant amino acid sequence mutations and their detection rates were as follows: M28V + L94P (A82G + T281C), 35.8% (29/81); M28V + V93A (A82G + T278C), 4.9% (4/81); R34K (G101A), 6.2% (5/81); N53D + L67S (A157G + T200C), 3.7% (3/81); F57S (T170C), 2.5% (2/81); and T72S (A214T), 2.5% (2/81).
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HPV Mutation Detail Information