HPV Mutation Detail Information

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Mutation Information
Mutation Site A793T
Mutation Type Nucleotide level
Gene/Protein/Region Type E7
Nucleotide_Mutation T78S
Genotype/Subtype HPV16
Viral Reference K02718.1
Country India
Literature Information
PubMed PMID 28988982
Disease Breast carcinoma; Cervical carcinoma
Published Year 2018
Journal Virus research
Title Phylogenetic analysis of Human papillomavirus 16 variants isolated from Indian Breast cancer patients showed difference in genetic diversity with that of cervical cancer isolates.
Author Islam S,Mazumder Indra D,Basu M,Roychowdhury A,Das P,Dasgupta H,Roy A,Alam N,Mondal RK,Roychoudhury S,Panda CK
Evidence In E7 region, amino acid T78S (793 A > T) variant has positive selection pressure (ω=1.4) in BC. But, no such codon was seen in CACX cases (Table 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation