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HIV Mutation Detail Information

> A77V Search Result


Mutation Information
Mutation Site A77V
Mutation Type Amino acid level
Gene/Protein/Region Type CA
Literature Information
PubMed PMID 32665593
Published Year 2020
Journal Nature communications
Title HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains.
Author Francis AC,Marin M,Singh PK,Achuthan V,Prellberg MJ,Palermino-Rowland K,Lan S,Tedbury PR,Sarafianos SG,Engelman AN,Melikyan GB
Evidence We curated (Supplementary Table 1) 46 CPSF6(+) RIGs from multiple cell types (HEK293T, HOS, MDM, and CD4+ T cells) and 30 CPSF6(−) RIGs from these same cells when infection occurred in the absence of the CA–CPSF6 interaction (i.e., N74D or A77V CA mutant viruses, or WT CA infection of CKO cells).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation