HIV Mutation Detail Information

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Mutation Information
Mutation Site A71V
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Literature Information
PubMed PMID 33175558
Published Year 2020
Journal Langmuir : the ACS journal of surfaces and colloids
Title Multiple Molecular Dynamics Simulations of the Inhibitor GRL-02031 Complex with Wild Type and Mutant HIV-1 Protease Reveal the Binding and Drug-Resistance Mechanism.
Author Wang R,Zheng Q
Evidence For instance, compared with the WT PR, L90M and V82F/I84V mutations cause the flaps to be more open,(60,61) while M46I and I50L/A71V mutations cause the flaps to be more closed.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation